In this article the author wrote about the proliferation of weapons of mass destruction in the Middle East. We have considered the reasons and motives of nuclear proliferation in the region. Details have been investigated external and internal factors of the Iranian nuclear program. Also described the impact of the Israeli nuclear program and other regional conflicts in the proliferation of weapons of mass destruction. There was also made a brief analysis of the security strategy of the United States.
Key words: weapons of mass destruction (WMD), United States, Middle East, Pakistan, India, Iran, Israel.