Summary: Biological tissues and organisms are quite diverse formations with different electrical resistances, which can change when exposed to an electric current. This makes it difficult to measure the parameters that characterize the electrical properties of organs and tissues. A perspective direction for diagnostics and biomedical studies of the permeability of biological tissue is the measurement of the dependence of the electrical conductivity of biological tissues on the frequencies of electric current. The amount of electrical conductivity depends on the number of free electric charges and their mobility. The basis of this study is the task of creating a measuring system and an algorithm for finding the most optimal form and parameters of an electrical signal, to provide the necessary depth and speed of penetration of pharmacological agents into biological tissue, and, consequently, to ensure the greatest effectiveness of the therapeutic effect. As a result of the experiments, the influence of the frequency and time of pulsed electrophoresis on the depth of introduction of a solution of iodine and diamond greens into adipose tissue was studied. The ranges of the most optimal frequencies for the introduction of pharmacological drugs in the electrically active state, in combination with the action of electric current, are established.
Keywords: electroconductivity, penetration of biological tissue, pharmacological preparations.
