Abstract. The paper presents the clinical and neuropsychological features in the middle aged adults - University staff living in the climate-geographic conditions of the Kyrgyz Republic, Bishkek. The examined individuals suffered from physical inactivity, violation of the mode of consumption of food, liquid, sleep disorders, accompanied by of the neurological symptoms and somatic diseases. High trait anxiety was diagnosed in 58,1% and depression in 54,8% of the teachers. In one third of patients physical fatigue with a decrease in daily activity was diagnosed.
Key words: clinical and neuropsychological features, middle aged adults, climatic and geographical conditions.